Inorganic carbon stimulates the metabolic routes related to the polyhdroxybutyrate production in a Synechocystis sp. strain (cyanobacteria) isolated from wastewater
Estel Rueda, Ana Álvarez-González, Joaquim Vila, Rubén Díez-Montero, Magdalena Grifoll, Joan Garcı́a
Abstract
were obtained. Gene expression analysis revelated that these conditions caused the overexpression of genes related to glycogen and PHB synthesis. Moreover, a positive correlation between the genes codifying for the glycogen phosphorylase, the acetyl-CoA reductase and the poly(3-hydroxyalkanoate) polymerase was found, meaning that PHB synthesis and glycogen catabolism are strongly related. These results provide an exhaustive evaluation of the effect of carbon on the PHB production and cyanobacterial metabolism.
Topics & Concepts
PolyhydroxybutyrateSynechocystisCyanobacteriaGlycogenPolyhydroxyalkanoatesBiochemistryChemistryGlycogen synthaseMetabolismCarbon fibersFood scienceBacteriaBiologyMaterials scienceGeneticsComposite materialComposite numberbiodegradable polymer synthesis and propertiesMicrobial Metabolic Engineering and BioproductionEnzyme Catalysis and Immobilization