Pirfenidone–flavonoid cocrystals with reduced solubility and dissolution rate
Lingshan Meng, Duanxiu Li, Yujing Zhu, Jianming Wang, Zongwu Deng, Hailu Zhang
Abstract
Two pirfenidone–flavonoid cocrystals with sustained release property were obtained.
Topics & Concepts
FlavonoidDissolutionPirfenidoneChemistrySolubilityOrganic chemistryMedicineAntioxidantInternal medicineIdiopathic pulmonary fibrosisLungCrystal structures of chemical compoundsCrystallography and molecular interactionsPhenothiazines and Benzothiazines Synthesis and Activities