Anticancer effects of solasonine: Evidence and possible mechanisms
YingZheng Wang, Tong Wang, Weidong Liu, Guangzhi Luo, Guangying Lu, Yanan Zhang, Huaxin Wang
Abstract
The effectiveness and safety of traditional Chinese medicine's active ingredients in anti-tumor effects have attracted widespread attention worldwide. Solasonine is the main anti-tumor component of the traditional Chinese medicine Solanum nigrum L, which can inhibit tumor cell proliferation, induce apoptosis, induce ferroptosis in tumor cells, and inhibit of tumor cell metastasis, thereby inhibiting tumor progression. Therefore, we summarized anti-tumor mechanisms and targets of solasonine to provide new ideas and theoretical basis for its further development and application.
Topics & Concepts
ApoptosisTumor cellsTraditional Chinese medicineCancer researchTraditional medicinePharmacologyMedicineBiologyPathologyBiochemistryAlternative medicinePotato Plant ResearchCancer, Lipids, and MetabolismCholangiocarcinoma and Gallbladder Cancer Studies