L-3-n-Butylphthalide Effectively Improves the Glymphatic Clearance and Reduce Amyloid-β Deposition in Alzheimer’s Transgenic Mice
Bo Zhang, Wei Li, Youguang Zhuo, Hui Xiang, Wenfeng Li, Hongying Liu, Longchang Xie, Qingchun Gao, Sheng Tan
Topics & Concepts
Glymphatic systemGenetically modified mouseParenchymaNeuroprotectionMorris water navigation taskPerivascular spaceAmyloid precursor proteinChemistryTransgeneMedicinePharmacologyPathologyAlzheimer's diseaseCerebrospinal fluidEndocrinologyNeurosciencePsychologyBiochemistryDiseaseHippocampal formationGeneCerebrospinal fluid and hydrocephalusTraumatic Brain Injury and Neurovascular DisturbancesNeurological Disease Mechanisms and Treatments