Litcius/Paper detail

A prime editor mouse to model a broad spectrum of somatic mutations in vivo

Zackery A. Ely, Nicolas Mathey‐Andrews, Santiago Naranjo, Samuel I. Gould, Kim L. Mercer, Gregory A. Newby, Christina M. Cabana, William M. Rideout, Grissel Cervantes-Jaramillo, Jennifer Khirallah, Katie Holland, Peyton B. Randolph, William A. Freed-Pastor, Jessie R. Davis, Zachary Kulstad, Peter M.K. Westcott, Lin Lin, Andrew V. Anzalone, Brendan Horton, Nimisha B. Pattada, Sean-Luc Shanahan, Zhongfeng Ye, Stefani Spranger, Qiaobing Xu, Francisco J. Sánchez‐Rivera, David R. Liu, Tyler Jacks

2023Nature Biotechnology58 citationsDOIOpen Access PDF

Topics & Concepts

Somatic cellBroad spectrumPrime (order theory)Spectrum (functional analysis)BiologyIn vivoGeneticsVirologyComputational biologyChemistryPhysicsMathematicsGeneCombinatoricsCombinatorial chemistryQuantum mechanicsCRISPR and Genetic EngineeringCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomics