Enantioselective electrosynthesis of inherently chiral calix[4]arenes <i>via</i> a cobalt-catalyzed aryl C–H acyloxylation
Liming Zhang, Chen Yang, Xinhai Wang, Taixin Yang, Dandan Yang, Yingchao Dou, Jun‐Long Niu
Abstract
An enantioselective electrosynthesis of inherent chiral calix[4]arenes via a cobalt enabled asymmetric C–H acyloxylation is revealed, which exhibits a broad substrate scope, excellent functional group tolerance, and high enantioselectivity.
Topics & Concepts
Enantioselective synthesisElectrosynthesisCobaltArylChemistrySubstrate (aquarium)CatalysisFunctional groupCombinatorial chemistryStereochemistryOrganic chemistryElectrochemistryPolymerPhysical chemistryElectrodeAlkylOceanographyGeologyCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsAxial and Atropisomeric Chirality Synthesis