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CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

Marian L. Burr, Christina E. Sparbier, Yih-Chih Chan, James C. Williamson, Katherine Woods, Paul A. Beavis, Enid Y.N. Lam, Melissa A. Henderson, Charles C. Bell, Sabine Stolzenburg, Omer Gilan, Stuart Bloor, Tahereh Noori, David W. Morgens, Michael C. Bassik, Paul J. Neeson, Andreas Behren, Phillip K. Darcy, Sarah‐Jane Dawson, Ilia Voskoboinik, Joseph A. Trapani, Jonathan Cebon, Paul J. Lehner, Mark A. Dawson

2017Nature954 citationsDOIOpen Access PDF

Topics & Concepts

RegulatorCell biologyCRISPRProgrammed cell deathLysosomeCas9CellBiologyCancer immunotherapyCancer cellChemistryCancer researchImmunotherapyCancerGeneBiochemistryGeneticsApoptosisEnzymeCancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmunotherapy and Immune Responses
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity | Litcius