Electrochemical-induced regioselective C-3 thiomethylation of imidazopyridines <i>via</i> a three-component cross-coupling strategy
Jiangwei Wen, Cong Niu, Kelu Yan, Xingda Cheng, Ruike Gong, Mengqian Li, Yongqiang Guo, Jianjing Yang, Hua Wang
Abstract
The electrochemical-induced regioselective C-3 thiomethylation of imidazopyridines has been initially accomplished <italic>via</italic> a three-component cross-coupling strategy using thiocyanate as the sulfur source and methanol as the methyl reagent.
Topics & Concepts
RegioselectivityElectrochemistryReagentComponent (thermodynamics)ChemistryCoupling (piping)Combinatorial chemistryMethanolSulfurThiocyanateOrganic chemistryElectrodeCatalysisMaterials sciencePhysical chemistryPhysicsThermodynamicsMetallurgySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsRadical Photochemical Reactions