QSAR modelling and molecular docking studies for anti-cancer compounds against melanoma cell line SK-MEL-2
Abdullahi Bello Umar, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba
Abstract
) the known inhibitor of the target (V600E-BRAF). These findings may be very helpful in early anti-cancer drug development.
Topics & Concepts
Quantitative structure–activity relationshipDocking (animal)Cancer cell linesChemistryStereochemistryComputational biologyCancerCancer cellBiologyMedicineInternal medicineNursingComputational Drug Discovery MethodsSynthesis and biological activityMicrobial Natural Products and Biosynthesis