Kolaflavanone of kolaviron selectively binds to subdomain 1B of human serum albumin: spectroscopic and molecular docking evidences
Ayodele O. Kolawole, Adejoke N. Kolawole, Kolawole A. Olofinsan, Olusola Olalekan Elekofehinti
Topics & Concepts
ChemistryHuman serum albuminHydrogen bondHydrophobic effectMolecular dynamicsQuenching (fluorescence)Docking (animal)Binding constantBioavailabilityStereochemistryMolecular modelPharmacokineticsBiophysicsComputational chemistryChromatographyBinding siteBiochemistryMoleculeFluorescenceOrganic chemistryPharmacologyQuantum mechanicsPhysicsBiologyMedicineNursingProtein Interaction Studies and Fluorescence AnalysisSurfactants and Colloidal SystemsChronic Lymphocytic Leukemia Research