Mechanistic Insights into the FeCl<sub>3</sub>-Catalyzed Oxidative Cross-Coupling of Phenols with 2-Aminonaphthalenes
Vlada Vershinin, Hagit Forkosh, Mor Ben‐Lulu, Anna Libman, Doron Pappo
Abstract
-biaryl compounds that are widely used as ligands and catalysts. Based on a comprehensive kinetic investigation, a catalytic cycle involving a ternary complex that binds to both the coupling partners and the oxidant during the key oxidative coupling step is postulated. Furthermore, the studies showed that the reaction is regulated by off-cycle acid-base and ligand exchange processes.
Topics & Concepts
CatalysisPhenolsCatalytic cycleOxidative coupling of methaneLigand (biochemistry)ChemistryOxidative phosphorylationTernary operationCombinatorial chemistryCoupling (piping)Primary (astronomy)Organic chemistryMaterials scienceComputer scienceBiochemistryProgramming languageReceptorAstronomyPhysicsMetallurgyAxial and Atropisomeric Chirality SynthesisCatalytic C–H Functionalization MethodsBiological and pharmacological studies of plants