Formamidation of a wide range of substituted and functionalized amines with CO and a base
Chunyan Zhang, Yushuang Zhang, Qianqian Liang, Guohui Zhang, Guohui Zhang, Wei Yang, Nanwen Li, Guiping Qin, Guoying Zhang, Guoying Zhang
Abstract
We have developed a base mediated formamidation of amines with CO under mild conditions, which allows for the synthesis of a wide range of aromatic and aliphatic formamides in high yields and gram amounts in the absence of a transition metal.
Topics & Concepts
FormamidesChemistryBase (topology)Transition metalCombinatorial chemistryCyclic aminesBase metalRange (aeronautics)Organic chemistryAmine gas treatingFormamideCatalysisMetallurgyMathematical analysisMaterials scienceWeldingComposite materialMathematicsCarbon dioxide utilization in catalysisAsymmetric Hydrogenation and CatalysisOrganometallic Complex Synthesis and Catalysis