Delivery of toll-like receptor 3 ligand poly(I:C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect in a mouse model
Yanqin Du, Xiaoli Yang, Jia Li, Viktoriya Sokolova, Shi Zou, Meihong Han, Hu Yan, K Wey, Mengji Lu, Ulf Dittmer, Dongliang Yang, Matthias Epple, Jun Wu
Topics & Concepts
Hepatitis B virusHBsAgAntibodyIn vivoHBeAgHepatitis BConjugated systemIn vitroVirologyMedicineMolecular biologyVirusImmunologyChemistryBiologyBiochemistryPolymerOrganic chemistryBiotechnologyHepatitis B Virus StudiesImmunotherapy and Immune ResponsesHepatitis Viruses Studies and Epidemiology