Litcius/Paper detail

Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer

Jashodeep Datta, Anna Bianchi, Iago De Castro Silva, Nilesh Deshpande, Long Cao, Siddharth Mehra, Samara P. Singh, Christine I. Rafie, Xiaodian Sun, Xi Chen, Xizi Dai, Antonio Colaprico, Prateek Sharma, Austin R. Dosch, Asha Pillai, Peter J. Hosein, Nagaraj S. Nagathihalli, Krishna V. Komanduri, Julie M. Wilson, Yuguang Ban, Nipun B. Merchant

2022Oncogene46 citationsDOI

Topics & Concepts

KRASBiologyCancer researchInnate immune systemTranscriptomeCancerTumor microenvironmentPancreatic cancerMyeloidImmune systemImmunologyColorectal cancerGeneticsGeneGene expressionPancreatic and Hepatic Oncology ResearchPhagocytosis and Immune RegulationPancreatitis Pathology and Treatment