Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy
Parinaz Fozouni, Sungmin Son, María Díaz de León Derby, Gavin J. Knott, Carley N Gray, Michael V. D’Ambrosio, Chunyu Zhao, Neil A. Switz, G. Renuka Kumar, Stephanie I. Stephens, Daniela Boehm, Chia-Lin Tsou, Jeffrey Shu, Abdul Bhuiya, Maxim Armstrong, Andrew R. Harris, Pei‐Yi Chen, Jeannette M. Osterloh, Anke Meyer‐Franke, Bastian Joehnk, Keith Walcott, Anita Sil, Charles Langelier, Katherine S. Pollard, Emily Crawford, Andreas S. Puschnik, Maíra Phelps, Amy Kistler, Joseph L. DeRisi, Jennifer A. Doudna, Daniel A. Fletcher, Mélanie Ott
Topics & Concepts
CRISPRBiologyRNAVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Gold standard (test)Computational biologyCoronavirus disease 2019 (COVID-19)MedicinePathologyDiseaseGeneInfectious disease (medical specialty)GeneticsInternal medicineCRISPR and Genetic EngineeringSARS-CoV-2 detection and testingBiosensors and Analytical Detection