Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport
William D. Ton, Yue Wang, Pengxin Chai, Cisloynny C. Beauchamp-Perez, Nicholas T. Flint, Lindsay G. Lammers, Hao Xiong, Kai Zhang, Steven M. Markus
Topics & Concepts
DyneinMicrotubuleDynactinCell biologyAllosteric regulationMotor proteinChemistryBiologyBiophysicsBiochemistryEnzymeMicrotubule and mitosis dynamicsPhotosynthetic Processes and MechanismsCellular transport and secretion