Activation of the kynurenine–aryl hydrocarbon receptor axis impairs the chondrogenic and chondroprotective effects of human umbilical cord-derived mesenchymal stromal cells in osteoarthritis rats
Xinwei Wang, Yingjie Zhao, Susu Li, Yueye Wang, Chengyan Jia, Xuezhi Yang, Siyu Li, Bingjie Zhang, Wei Wei, Yan Chang
Topics & Concepts
Mesenchymal stem cellChondrogenesisAryl hydrocarbon receptorChemistryStromal cellOsteoarthritisCartilageCell biologyCancer researchPharmacologyImmunologyMedicineTranscription factorBiologyAnatomyBiochemistryPathologyAlternative medicineGeneFibromyalgia and Chronic Fatigue Syndrome ResearchExercise and Physiological ResponsesStress Responses and Cortisol