A rapid “on–off–on” mitochondria-targeted phosphorescent probe for selective and consecutive detection of Cu<sup>2+</sup> and cysteine in live cells and zebrafish
Peipei Deng, Yongyan Pei, Mengling Liu, Wenzhu Song, Mengru Wang, Feng Wang, Chunxian Wu, Li Xu
Abstract
An iridium(<sc>iii</sc>) complex-based mitochondria targeting phosphorescent probe for selectively detecting Cu<sup>2+</sup> and Cys in aqueous solution, living cells and zebrafish has been developed.
Topics & Concepts
PhosphorescenceDetection limitCysteineChemistryIridiumLuminescencePhotochemistryLigand (biochemistry)FluorescenceChelationPyridineCombinatorial chemistryMaterials scienceInorganic chemistryReceptorBiochemistryOrganic chemistryChromatographyEnzymeCatalysisQuantum mechanicsPhysicsOptoelectronicsMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniquesLuminescence and Fluorescent Materials