Nanoencapsulation of Phenolic Extracts from Native Potato Clones (Solanum tuberosum spp. andigena) by Spray Drying
Carlos A. Ligarda-Samanez, David Choque-Quispe, Elibet Moscoso-Moscoso, Henry Palomino-Rincón, Fredy Taipe-Pardo, John Peter Aguirre Landa, José Carlos Arévalo Quijano, Jenny C. Muñoz-Saenz, Uriel Rigoberto Quispe Quezada, Mary L. Huamán-Carrión, Edgar Gutiérrez-Gómez, Reynaldo Sucari León, Rober Aníbal Luciano Alipio, Judy M. Muñoz-Saenz, R. Gutiérrez
Abstract
Native potato clones grown in Peru contain bioactive compounds beneficial to human health. This study aimed to optimize the spray-drying nanoencapsulation of native potato phenolic extracts utilizing a central composite design and response surface methodology, obtaining the optimal treatment to an inlet temperature of 120 °C and an airflow of 141 L/h in the nano spray dryer B-90, which allowed maximizing the yield of encapsulation, antioxidant capacity (DPPH), encapsulation efficiency (EE), total phenolic compounds, and total flavonoids; on the other hand, it allowed minimizing hygroscopicity, water activity (Aw), and moisture. Instrumental characterization of the nanocapsules was also carried out, observing a gain in lightness, reddening of the color, and spherical nanoparticles of heterogeneous size (133.09-165.13 nm) with a negative ζ potential. Thermal, infrared, and morphological analyses confirmed the encapsulation of the core in the wall materials. Furthermore, an in vitro release study of phenolic compounds in an aqueous solution achieved a maximum value of 9.86 mg GAE/g after 12 h. Finally, the obtained nanocapsules could be used in the food and pharmaceutical industry.