Litcius/Paper detail

Influence of pig farming on human Gut Microbiota: role of airborne microbial communities

Julia Moor, Tsering Wüthrich, Suzanne Aebi, Nadezda Kryuchkova-Mostacci, Gudrun Overesch, Anne Oppliger, Markus Hilty

2021Gut Microbes30 citationsDOIOpen Access PDF

Abstract

than workers exposed to cattle. We also found that the microbial compositions of pig workers' stool samples shared extensive fractions with the samples from their pigs. We also identified amplicon sequencing variants (ASVs) in the airborne microbiota which were likely involved in zoonotic transmission events.We hypothesize that ASVs originating from pig feces are aerosolized and, through breathing, get trapped in the pig farm workers' upper respiratory tract from where they can get swallowed. Consequently, some of the animal associated ASVs are transferred into the gastrointestinal tracts (GITs) which leads to changes in the composition of the human gut microbiota. The importance of this finding for human health must be investigated further.

Topics & Concepts

BiologyFecesAmplicon sequencingClostridialesMicrobiologyMicrobiomePyrosequencingVeterinary medicine16S ribosomal RNAGut floraZoologyClostridiaceaeBacteriaGeneticsImmunologyGeneMedicineToxinGut microbiota and healthClostridium difficile and Clostridium perfringens researchProbiotics and Fermented Foods