Therapeutic drug monitoring-based precision dosing of oral targeted therapies in oncology: a prospective multicenter study
Stefanie L. Groenland, Ruben A.G. van Eerden, Kim Westerdijk, Marinda Meertens, Stijn L.W. Koolen, Dirk Jan A. R. Moes, Nanné K. de Vries, Hilde Rosing, H-M.M.B. Otten, Annelie Vulink, Ingrid M.E. Desar, Alex L.T. Imholz, Hans Gelderblom, Nielka P. van Erp, Jos H. Beijnen, Ron H.J. Mathijssen, Alwin D. R. Huitema, Neeltje Steeghs
Topics & Concepts
MedicineDosingCminPharmacokineticsConfidence intervalInternal medicineConcomitantDrugProspective cohort studyTherapeutic drug monitoringCmaxPharmacologyStatistical Methods in Clinical TrialsCancer Treatment and PharmacologyPharmacogenetics and Drug Metabolism