S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function
Jing Zhang, Shuhua Chen, Hong Xiang, Jie Xiao, Shaoli Zhao, Zhihao Shu, Yanfei Chai, Jie Ouyang, Huiqin Liu, Xueweng Wang, Qisheng Quan, Jianing Fan, Peng Gao, Alex F. Chen, Hongwei Lü
Topics & Concepts
RHOAROCK1Epithelial–mesenchymal transitionCancer researchEndothelial stem cellCell biologyCTGFSignal transductionBiologyChemistryMedicineInternal medicineDownregulation and upregulationIn vitroBiochemistryReceptorGrowth factorGeneChronic Kidney Disease and DiabetesCancer, Hypoxia, and MetabolismBirth, Development, and Health