Molecular mechanisms of the antibacterial activity of polyimide fibers in a skin-wound model with Gram-positive and Gram-negative bacterial infection <i>in vivo</i>
Xia Yang, Wei Ma, Hua Lin, Shengxiang Ao, Haoru Liu, Hao Zhang, Wanqi Tang, Hongyan Xiao, Fangjie Wang, Junyu Zhu, Daoyan Liu, Shujun Lin, Ying Zhang, Zhongfu Zhou, Changbin Chen, Huaping Liang
Abstract
A novel natural polyimide fiber was identified and displayed significant antibacterial activity against E. coli and MRSA in vitro and in vivo, may act as a promising candidate for antimicrobial material for trauma and surgical applications.
Topics & Concepts
GramIn vivoGram-negative bacteriaGram-positive bacteriaBacteriaMicrobiologyAntibacterial activityPolyimideBiologyChemistryAntibioticsOrganic chemistryBiochemistryEscherichia coliBiotechnologyGeneticsLayer (electronics)GeneAntimicrobial agents and applicationsWound Healing and TreatmentsSurgical Sutures and Adhesives