Chemotherapy-induced neurotoxicity in the treatment of gynecological cancers: State of art and an innovative approach for prevention
Ester Oneda, Chiara Abeni, Laura Zanotti, Elisabetta Zaina, Sara Bighè, Alberto Zaniboni
Abstract
Chemo care device is a regional cooling system that lowers the temperature of the hands and feet to reduce the flow of chemotherapy into the capillaries. We used hilotherapy during chemotherapy infusion to prevent the onset of CIPN. Updated data from 44 ovarian cancer patients treated with 6 cycle of CP show that hilotherapy was well tolerated; only two patients (4.5%) stopped hilotherapy because of cold intolerance, and only one patient (2.2%) experienced grade ≥ 2 CIPN.
Topics & Concepts
MedicineNeurotoxicityChemotherapyIntensive care medicineOncologySurgeryInternal medicineToxicityCancer Treatment and PharmacologyCancer-related cognitive impairment studiesChemotherapy-induced cardiotoxicity and mitigation