Advances in C(<i>sp</i><sup>2</sup>)−H/C(<i>sp</i><sup>2</sup>)−H Oxidative Coupling of (Hetero)arenes Using 3d Transition Metal Catalysts
Sadhna Bansal, Anand B. Shabade, Benudhar Punji
Abstract
Abstract C−H/C−H oxidative coupling has emerged as a straightforward and powerful technique for the construction of (hetero)biaryls, with substantial application to drug discovery, agrochemicals, biology, and material sciences. Mainly aryl‐aryl, aryl‐heteroaryl, and heteroaryl‐heteroaryl couplings via double C( sp 2 )−H activation using 4d or 5d noble transition metal catalysts have been extensively studied. Considering the earth‐abundant and inexpensive nature of 3d transition metals, the sustainable development of C( sp 2 )−H/C( sp 2 )−H oxidative coupling employing such metal catalysts has gained significant attention. In this review, we present a comprehensive overview of C( sp 2 )−H/C( sp 2 )−H oxidative coupling of (hetero)arenes catalyzed by 3d transition metals. magnified image