<sup>15</sup>N-Azides as practical and effective tags for developing long-lived hyperpolarized agents
Junu Bae, Guannan Zhang, Hyejin Park, Warren S. Warren, Qiu Wang
Abstract
This work demonstrates that 15 N-labeled azides are practical and effective tags for developing long-lived hyperpolarized MRI agents and can offer hyperpolarization lifetimes up to 9.8 min at 1 T and high polarization levels up to 11.6% in water.
Topics & Concepts
ChemistryCombinatorial chemistryAdvanced NMR Techniques and ApplicationsChemical Reaction MechanismsClick Chemistry and Applications