Development and Progression of Bovine Respiratory Disease Measured Using Clinical Respiratory Scoring and Thoracic Ultrasonography in Preweaned Calves on Dairy Farms in the United Kingdom: A Prospective Cohort Study
George Lindley, Nicola Blackie, D.C. Wathes, Richard Booth
Abstract
The respiratory health of preweaned calves is an important determinant of their health, welfare, and future performance. This prospective cohort study measured bovine respiratory disease (BRD) on 16 dairy farms, including 476 calves in South-west England. Wisconsin and California respiratory scoring and thoracic ultrasonography were performed repeatedly at 7 ± 0.89 day intervals (mean ± SD) at 0-56 days of age (n = 3344 examinations). Cases were localized to the upper or lower respiratory tract, or both, and classified as new, repeat, or chronic. Prevalence and incidence were calculated. Multivariate modeling of factors associated with repeated measurements was performed. Increasing age (OR = 1.05, 95% CI 1.04-1.06) and fecal score (Score 2, OR = 1.78, 95% CI 1.14-2.77) were associated with a lower odds of a healthy BRD subtype, whereas increasing serum total protein (OR = 0.97, 95% CI 0.96-0.99) was protective. Older (OR 1.08, 95% CI 1.06-1.09), male (OR 1.69, 95% CI 1.01-2.84) calves with elevated Wisconsin respiratory scores (≥5, OR 5.61, 95% CI 3.38-9.30) were more likely to have elevated thoracic ultrasound scores. BRD remains common in calves born in UK dairy herds, requiring precise identification and management if preweaning health is to be optimized.