A review on recent advances for the synthesis of bioactive pyrazolinone and pyrazolidinedione derivatives
Aly A. Abd-Ella, Saoud A. Metwally, Mokhtar A. Abd ul‐Malik, Yasser A. El‐Ossaily, Fathy M. Abd Elrazek, Safwat A. Aref, Youssra A. Naffea, Shaban A. A. Abdel‐Raheem
Abstract
Oxo derivatives of pyrazolines and pyrazolidines are important heterocyclic compounds due to their unique biological activities and have been widely applied in pharmaceutical and agromedical fields. In this review, we provide an account of some recent advances in the field of pyrazolone chemistry, specifically on the reported synthesis methods of pyrazolinone (3-oxo-1,2-dihydropyrazole) and 3,5-pyrzolidinediones (3,5-dioxotetrahydropyrazoles) derivatives.
Topics & Concepts
ChemistryCombinatorial chemistryPyrazoloneOrganic chemistryNanotechnologyMaterials scienceSynthesis and biological activitySynthesis of heterocyclic compoundsSynthesis and Reactions of Organic Compounds