Litcius/Paper detail

Endotypes of atopic dermatitis

Nanna Fyhrquist, Ying Yang, Piia Karisola, Harri Alenius

2025Journal of Allergy and Clinical Immunology44 citationsDOIOpen Access PDF

Abstract

22-driven responses, genetic factors, and microbial interactions. Recognizing these endotypes has become essential for advancing personalized treatments because each subtype responds differently to immune-modulating therapies. Current treatment options, such as moisturizers, immunosuppressants, and biologics, show varied efficacy across AD endotypes, underscoring the need for more precise, endotype-specific approaches. Emerging molecular profiling technologies offer promising avenues to identify distinct biomarkers, refining AD classification and paving the way for more targeted treatments and improved patient outcomes.

Topics & Concepts

Atopic dermatitisDermatologyMedicineDermatology and Skin DiseasesFood Allergy and Anaphylaxis ResearchUrticaria and Related Conditions