A {Cd<sub>4</sub>Cl<sub>2</sub>O<sub>14</sub>} cluster functionalized sandwich-type tungstoarsenate as a conformation modulator for misfolding Aβ peptides
Jiai Hua, Xueman Wei, Xiang Ma, Jinzhe Jiao, Binghui Chai, Chenbin Wu, Changli Zhang, Yulan Niu
Abstract
A nanoscale polyoxometalate {[H 2 dap] 6 [Cd 4 Cl 2 (B-α-AsW 9 O 34 ) 2 ]} based on tetra-Cd cluster sandwiched trivacant Keggin-type tungstoarsenate was successfully synthesized, which it can modulate the β-sheet-rich fibrils of Aβ peptide efficiently.
Topics & Concepts
PolyoxometalateCluster (spacecraft)CrystallographyPeptideTetraChemistryNanoscopic scaleStereochemistryMaterials scienceNanotechnologyBiochemistryMedicinal chemistryCatalysisComputer scienceProgramming languagePolyoxometalates: Synthesis and ApplicationsMetal-Organic Frameworks: Synthesis and ApplicationsNanocluster Synthesis and Applications