Silver-catalyzed cascade cyclization and functionalization of <i>N</i>-aryl-4-pentenamides: an efficient route to γ-lactam-substituted quinone derivatives
Zeguo Fang, Lin Xie, Liang Wang, Qian Zhang, Dong Li
Abstract
The synthesis of γ-lactam and related 2-oxazolidinone substituted quinone derivatives through a Ag 2 O-catalyzed cascade cyclization and functionalization of N -ary-4-pentenamides and N -aryl allyl carbamates has been developed.
Topics & Concepts
QuinoneChemistryArylLactamSurface modificationSubstrate (aquarium)CatalysisCombinatorial chemistryCascadeAryl radicalStereochemistryOrganic chemistryPhysical chemistryChromatographyGeologyOceanographyAlkylCatalytic C–H Functionalization MethodsBioactive Compounds and Antitumor AgentsSynthesis of Indole Derivatives