Recent strategies for nano-based PTT combined with immunotherapy: from a biomaterial point of view
Xingyue Huang, Yang Lu, Mingxue Guo, Shouying Du, Ning Han
Abstract
vaccines; 3) nano-based PTT synergized with immune checkpoint blockade or other regulators to relieve the ITM; 4) nano-based PTT combined with CAR-T therapy or cytokine therapy for tumor treatment. The characteristics of various photothermal agents and nanoplatforms as well as the immunological mechanisms for the synergism were also introduced in detail. Finally, we discussed the existing challenges and future prospects in combined PTT and immunotherapy.
Topics & Concepts
ImmunotherapyMedicineCancer immunotherapyPhotothermal therapyImmune systemTumor microenvironmentImmunogenicityCancerImmunologyCancer researchInternal medicineNanotechnologyMaterials scienceNanoplatforms for cancer theranosticsImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers