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Three-component photoredox 1,2-alkylamination of styrenes with alkanes and nitrogen nucleophiles <i>via</i> C(sp<sup>3</sup>)–H bond cleavage

Jing Huang, Yunyan Liang, Xuan‐Hui Ouyang, Yuting Xiao, Jing‐Hao Qin, Ren‐Jie Song, Jin‐Heng Li

2021Organic Chemistry Frontiers33 citationsDOI

Abstract

A three-component photoredox 1,2-alkylamination of styrenes involving functionalization of C(sp 3 )–H bonds in alkyl halides instead of functionalization of C-halogen bonds is disclosed.

Topics & Concepts

ChemistryNucleophileNitrogenCleavage (geology)Bond cleavageComponent (thermodynamics)Medicinal chemistryOrganic chemistryPhotochemistryCatalysisThermodynamicsPhysicsFracture (geology)Geotechnical engineeringEngineeringRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsFluorine in Organic Chemistry
Three-component photoredox 1,2-alkylamination of styrenes with alkanes and nitrogen nucleophiles <i>via</i> C(sp<sup>3</sup>)–H bond cleavage | Litcius