A case of safe and durable focal pulsed-field electroporation treatment of outflow tract premature ventricular contractions
René Worck, Martin Haugdal, Arne Johannessen, Morten Lock Hansen, Martin H. Ruwald, Jim Hansen
Abstract
Key Findings▪The case describes use of Focal Pulsed Field Electroporation (F-PFE) to ablate PVCs originating in the RVOT-LVOT-RCC zone▪F-PFE electroporation was carried out using low to medium energy delivery preceded by intravenous nitrates to prevent coronary spasm and under real time ICE-imaging.▪Electroporation was applied solely in the RVOT and was safe without any short- or long-term adverse events▪48 h Holter follow up after 2 months confirmed reduction of PVC burden from 11% to less than 0.01%▪F-PFE safely, efficaciously, and durably eradicated PVCs in this case ▪The case describes use of Focal Pulsed Field Electroporation (F-PFE) to ablate PVCs originating in the RVOT-LVOT-RCC zone▪F-PFE electroporation was carried out using low to medium energy delivery preceded by intravenous nitrates to prevent coronary spasm and under real time ICE-imaging.▪Electroporation was applied solely in the RVOT and was safe without any short- or long-term adverse events▪48 h Holter follow up after 2 months confirmed reduction of PVC burden from 11% to less than 0.01%▪F-PFE safely, efficaciously, and durably eradicated PVCs in this case