Litcius/Paper detail

Monkeypox mathematical model with surveillance as control

Unknown authors

2023Communications in Mathematical Biology and Neuroscience15 citationsDOIOpen Access PDF

Abstract

A compartmental mathematical model of the transmission dynamics of the monkeypox virus (MPXV) was developed and analyzed. The model incorporates proper surveillance and contact tracing as effective controls. The equilibrium states of the model were obtained and analyzed both locally and globally. The effective reproduction number, R m was obtained and the sensitivity of the model parameters were studied using R m as the threshold of transmission. When the infection becomes endemic, R m ≈1, the model exhibits a backward bifurcation but R m < 1 which means that the interventions tend to MPXV containment. Numerical simulations to bespeak our findings and discussions are provided. Our result shows that surveillance and contact tracing are effective for the containment of MPXV in the absence of a perfect vaccine.

Topics & Concepts

MonkeypoxTransmission (telecommunications)Containment (computer programming)Basic reproduction numberBifurcationEpidemic modelSensitivity (control systems)Computer sciencePhysicsBiologyDemographyEngineeringTelecommunicationsPopulationQuantum mechanicsRecombinant DNAGeneSociologyVacciniaElectronic engineeringNonlinear systemBiochemistryProgramming languageBacteriophages and microbial interactionsMathematical and Theoretical Epidemiology and Ecology ModelsPoxvirus research and outbreaks