How do nocebo effects in placebo groups of randomized controlled trials provide a possible explicative framework for the COVID-19 pandemic?
Martina Amanzio, Giuseppina Elena Cipriani, Massimo Bartoli
Abstract
: The nocebo effect could explain the presence of strong resistance in European countries to immunization with a vaccine perceived as less effective, compared to others. Increased awareness of the nocebo effect would be relevant as it could lead to a greater participation in the vaccination campaign and in protecting individuals against SARS-CoV-2 infection.
Topics & Concepts
MedicineRandomized controlled trialNocebo EffectCoronavirus disease 2019 (COVID-19)PandemicPlaceboSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakClinical trialNoceboPerspective (graphical)Alternative medicineIntensive care medicineInternal medicineDiseasePathologyOutbreakInfectious disease (medical specialty)Artificial intelligenceComputer sciencePain Management and Placebo EffectEmpathy and Medical EducationIntramuscular injections and effects