Prospects of nanoparticle-based radioenhancement for radiotherapy
Lukas R. H. Gerken, Maren E. Gerdes, Martin Pruschy, Inge K. Herrmann
Abstract
nanoparticle radioenhancers and highlight the importance of catalytic activity. This review provides a concise overview on the knowledge of nanoparticle radioenhancement mechanisms and their quantification. It critically discusses potential radioenhancer candidate materials and general design criteria for different radiation therapy modalities, and concludes with research priorities in order to advance the development of nanomaterials, to enhance the efficacy of radiotherapy and to increase at the same time the therapeutic window.
Topics & Concepts
Radiation therapyNanomaterialsNanotechnologyPillarNanoparticleTherapeutic windowMaterials scienceMedical physicsMedicineEngineeringSurgeryPharmacologyStructural engineeringRadiation Therapy and DosimetryAdvanced Radiotherapy TechniquesBoron Compounds in Chemistry