Resolving Oxygenation Pathways in Manganese-Catalyzed C(sp<sup>3</sup>)–H Functionalization via Radical and Cationic Intermediates
Marco Galeotti, Laia Vicens, Michela Salamone, Miguel Costas, Massimo Bietti
Abstract
)-H oxidation can take place via a cationic intermediate and that this path can become exclusive in governing product formation, expanding the available toolbox of aliphatic C-H bond oxygenations. The implications of these findings are discussed in the framework of the development of synthetically useful C-H functionalization procedures and the associated mechanistic features.
Topics & Concepts
ChemistryCationic polymerizationManganeseCatalysisSurface modificationOxygenationMedicinal chemistryPhotochemistryCombinatorial chemistryPolymer chemistryOrganic chemistryPhysical chemistryEcologyBiologyCatalytic C–H Functionalization MethodsMetal-Catalyzed Oxygenation MechanismsSynthesis and Catalytic Reactions