Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells
Alberta Palazzo, Héctor Hernández‐Vargas, Delphine Goehrig, Jean‐Jacques Médard, David Vindrieux, Jean‐Michel Flaman, David Bernard
Topics & Concepts
SenescenceCancer researchMalignant transformationBiologyTranscriptomePhenotypeCancer cellCancerCellMelanomaGene signatureTumor progressionCell biologyGeneGeneticsGene expressionTelomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomicsImmunotherapy and Immune Responses