Myxococcus xanthus Predation of Gram-Positive or Gram-Negative Bacteria Is Mediated by Different Bacteriolytic Mechanisms
Kirstin I. Arend, Janka J. Schmidt, Tim Bentler, Carina Lüchtefeld, Daniel Eggerichs, Hannah M. Hexamer, Christine Kaimer
Abstract
, aiming to dissect the molecular mechanisms of prey cell lysis. In this study, we addressed the role of secreted bacteriolytic proteins, as well as potential mechanistic differences in the predation of Gram-positive and Gram-negative bacteria. Our observation shows that secreted enzymes are sufficient for killing and degrading Gram-positive species, but that cell-associated mechanisms may play a major role for killing Gram-negative and Gram-positive prey on fast timescales.
Topics & Concepts
Myxococcus xanthusGramGram-negative bacteriaBacteriaBiologyGram-positive bacteriaMicrobiologyPredationEcologyEscherichia coliGeneticsGeneMutantAntibiotic Resistance in BacteriaVibrio bacteria research studiesBacterial Genetics and Biotechnology