18F-MFBG PET/CT and MRI in Identifying Brain Metastases in a Posttreatment Neuroblastoma Patient
Peipei Wang, Tuo Li, Hongming Zhuang, Fang Li, Hongli Jing
Abstract
ABSTRACT: A 7-year-old girl with known brain metastasis from neuroblastoma developed new onset of severe headache. A brain MRI confirmed known metastasis in the right frontal lobe of the brain without new abnormalities. The patient was enrolled in a clinical trial using 18 F-MFBG PET/CT to evaluate patients with neuroblastoma. The images confirmed abnormal activity in the known lesion in the right frontal lobe. In addition, the PET showed additional foci of abnormal activity in the left cerebellopontine region. A follow-up brain MRI study acquired 4 months later revealed abnormal signals in the same region.
Topics & Concepts
MedicineNeuroblastomaLesionRadiologyFrontal lobeTemporal lobeMagnetic resonance imagingBrain metastasisMetastasisNuclear medicinePathologyEpilepsyInternal medicineCancerGeneticsBiologyPsychiatryCell cultureNeuroblastoma Research and TreatmentsAdrenal and Paraganglionic TumorsGlioma Diagnosis and Treatment