Synthesis and enantioseparation of proline-derived helical polyacetylenes as chiral stationary phases for HPLC
Ge Shi, Xiao Dai, Yue Zhou, Jie Zhang, Jun Shen, Xinhua Wan
Abstract
Proline-derived aliphatically substituted polyacetylenes with stable helical conformations exhibit an excellent enantioseparation ability as chiral stationary phases of HPLC.
Topics & Concepts
ProlineHigh-performance liquid chromatographyChiral stationary phaseChemistryChiral column chromatographyChromatographyEnantioselective synthesisStereochemistryOrganic chemistryAmino acidBiochemistryCatalysisAnalytical Chemistry and ChromatographyMolecular spectroscopy and chiralityAdvanced NMR Techniques and Applications