pH-responsive sparfloxacin/Fe3+ nanoparticles eradicate intratumoral bacteria and activate ferroptosis for enhanced antitumor immunotherapy in breast cancer
Zhiting Sun, Ming Xu, Lu Nie, Changrong Wang, Jing Wu, Weiwei Wang, Shengbin Shi, Huijuan Song
Topics & Concepts
Cancer researchBreast cancerTumor microenvironmentImmunotherapyChemistryMetastasisImmune systemCancer immunotherapyCancer cellCancerCytotoxic T cellPancreatic cancerGlutathioneCytotoxicityMedicineLipid peroxidationMicrovesiclesApoptosisTumor-associated macrophageBacteriaImmunogenic cell deathTumor progressionImmunityLung cancerCellImmunologyMammary tumorFerroptosis and cancer prognosisNanoplatforms for cancer theranosticsImmune cells in cancer