Peptoid-based siderophore mimics as dinuclear Fe<sup>3+</sup> chelators
Assunta D’Amato, Pritam Ghosh, Chiara Costabile, Giorgio Della Sala, Irene Izzo, Galia Maayan, Francesco De Riccardis
Abstract
A practical synthesis of preorganized tripodal enterobactin/corynebactin-type ligands (consisting of a <italic>C</italic><sub>3</sub>-symmetric macrocyclic peptoid core, three catecholamide coordinating units, and C<sub>2</sub>, C<sub>4</sub>, and C<sub>6</sub> spacers) and their unique Fe<sup>3+</sup> complexes is reported.
Topics & Concepts
PeptoidChemistryStereochemistryEnterobactinChelationGroup 2 organometallic chemistryCrystallographySiderophoreCombinatorial chemistryMoleculePeptideOrganic chemistryBiochemistryGeneMicrobial Metabolites in Food BiotechnologyLegume Nitrogen Fixing SymbiosisCarbohydrate Chemistry and Synthesis