Iodine-mediated electrochemical C(sp<sup>3</sup>)–H cyclization: the synthesis of quinazolinone-fused N-heterocycles
Yan Zhang, Zhenghong Zhou, Zhibin Li, Kangfei Hu, Zhenggen Zha, Zhiyong Wang
Abstract
)-H cyclization was developed under mild conditions. A variety of functionalized quinazolinone-fused N-heterocycles can be obtained with good to excellent yields by virtue of this method. The reaction features a broad substrate scope and scalability, and is metal-free and chemical oxidant-free.
Topics & Concepts
QuinazolinoneElectrochemistryChemistryIodineCombinatorial chemistrySubstrate (aquarium)Organic chemistryElectrodePhysical chemistryGeologyOceanographyQuinazolinone synthesis and applicationsCatalytic C–H Functionalization MethodsRadical Photochemical Reactions