Regio- and Stereoselective Cobalt-Catalyzed Hydroboration of Vinylcyclopropanes to Access Homoallylic Boronates
Dongpo Lu, Chen‐Hui Chen, Lixuan Zheng, Jiale Ying, Zhan Lu
Abstract
Herein, a cobalt-catalyzed hydroboration of vinylcyclopropanes was reported to access the corresponding homoallylic boronates with excellent regio- and stereoselectivity. This reaction features a broad substrate scope and could be carried out on a gram scale. The possible mechanism and models for selectivity have been proposed.
Topics & Concepts
HydroborationChemistryStereoselectivityCobaltSelectivitySubstrate (aquarium)CatalysisCombinatorial chemistryScope (computer science)StereochemistryOrganic chemistryGeologyProgramming languageOceanographyComputer scienceOrganoboron and organosilicon chemistryCyclopropane Reaction MechanismsCatalytic C–H Functionalization Methods