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Structural and mechanistic insights into the inhibition of amyloid-β aggregation by Aβ39-42 fragment derived synthetic peptides

Akshay Kapadia, Krishna K. Sharma, Indresh Kumar Maurya, Varinder Singh, Madhu Khullar, Rahul Jain

2020European Journal of Medicinal Chemistry17 citationsDOI

Topics & Concepts

ChemistryThioflavinPeptideNeurotoxicityBiophysicsBiochemistryMonomerAmyloid (mycology)StereochemistryAlzheimer's diseaseToxicityOrganic chemistryInorganic chemistryPathologyPolymerDiseaseBiologyMedicineAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery Methods
Structural and mechanistic insights into the inhibition of amyloid-β aggregation by Aβ39-42 fragment derived synthetic peptides | Litcius