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Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19

Peng Luo, Yuanfang Ding, Yuan He, Dafeng Chen, Qing He, Zufeng Huang, Shian Huang, Wei Lei

2022Medicine14 citationsDOIOpen Access PDF

Abstract

ABSTRACT: A global public health crisis caused by the 2019 novel coronavirus disease (COVID-19) leads to considerable morbidity and mortality, which bring great challenge to respiratory medicine. Hydrogen-oxygen therapy contributes to treat severe respiratory diseases and improve lung functions, yet there is no information to support the clinical use of this therapy in the COVID-19 pneumonia.A retrospective study of medical records was carried out in Shishou Hospital of Traditional Chinese Medicine in Hubei, China. COVID-19 patients (aged ≥ 30 years) admitted to the hospital from January 29 to March 20, 2020 were subjected to control group (n = 12) who received routine therapy and case group (n = 12) who received additional hydrogen-oxygen therapy. The clinical characteristics of COVID-19 patients were analyzed. The physiological and biochemical indexes, including immune inflammation indicators, electrolytes, myocardial enzyme profile, and functions of liver and kidney, were examined and investigated before and after hydrogen-oxygen therapy.The results showed significant decreases in the neutrophil percentage and the concentration and abnormal proportion of C-reactive protein in COVID-19 patients received additional hydrogen-oxygen therapy.This novel therapeutic may alleviate clinical symptoms of COVID-19 patients by suppressing inflammation responses.

Topics & Concepts

MedicineMedical recordRetrospective cohort studyInternal medicineDiseaseIntensive care medicineInflammationRespiratory systemImmune systemRespiratory diseasePublic healthAdverse effectHospital medicineLungEmergency medicineMEDLINETraditional Chinese medicineSeverity of illnessClinical significanceHydrogen's biological and therapeutic effectsSulfur Compounds in BiologyMedicinal Plants and Bioactive Compounds