Manganese-promoted reductive cross-coupling of disulfides with dialkyl carbonates
Chao‐Peng Zhang, Tian‐Zhang Wang, Yu‐Feng Liang
Abstract
Manganese is a cheap and environmentally friendly metal on Earth. Herein, we report a manganese-promoted reductive cross-coupling using easily available and odorless disulfides as thiolating agents in an excellent 100% sulfur atom economy. The protocol featured a broad substrate scope, including various alkyl disulfides and excellent functional group compatibility, constructing diverse thioethers under simple conditions. Ultimately, thioethers can be prepared in gram-scale reactions and further transformed into structurally complex molecules.
Topics & Concepts
ManganeseChemistryCoupling (piping)Inorganic chemistryPolymer chemistryCombinatorial chemistryMaterials scienceOrganic chemistryMetallurgySulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCarbon dioxide utilization in catalysis