Rapamycin suppresses neuroinflammation and protects retinal ganglion cell loss after optic nerve crush
Feifei Wang, Yuning Song, Peiyu Liu, Fangli Ma, Zhida Peng, Yulian Pang, Haijian Hu, Ling Zeng, Hongdou Luo, Xu Zhang
Topics & Concepts
PyroptosisRetinal ganglion cellInflammasomeOptic nervePI3K/AKT/mTOR pathwayRetinaCell biologyNeuroinflammationRetinalCaspase 1Crush injuryNeuroscienceGlaucomaBiologySignal transductionChemistryReceptorMedicineImmunologyInflammationBiochemistrySurgeryGlaucoma and retinal disordersInflammasome and immune disordersOcular Diseases and Behçet’s Syndrome